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Desethyl Hydroxychloroquine-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Desethyl Hydroxychloroquine-d4图片
CAS NO:1854126-47-8
包装与价格:
包装价格(元)
500 μg电议
1mg电议
5mg电议

产品介绍
An internal standard for the quantification of desethyl hydroxychloroquine
Cas No.1854126-47-8
别名Desethylhydroxychloroquine-d4
Canonical SMILESClC1=CC2=C(C=C1)C(NC(C)CCCNC([2H])([2H])C([2H])([2H])O)=CC=N2
分子式C16H18ClD4N3O
分子量311.8
溶解度DMF: Soluble,DMSO: Soluble,Methanol: Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Desethyl hydroxychloroquine-d4is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .1It is formedviathe desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.

1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018)