CAS NO: | 1854126-47-8 |
包装 | 价格(元) |
500 μg | 电议 |
1mg | 电议 |
5mg | 电议 |
Cas No. | 1854126-47-8 |
别名 | Desethylhydroxychloroquine-d4 |
Canonical SMILES | ClC1=CC2=C(C=C1)C(NC(C)CCCNC([2H])([2H])C([2H])([2H])O)=CC=N2 |
分子式 | C16H18ClD4N3O |
分子量 | 311.8 |
溶解度 | DMF: Soluble,DMSO: Soluble,Methanol: Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Desethyl hydroxychloroquine-d4is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .1It is formedviathe desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8. 1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018) |