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1,2-Dioleoyl-sn-glycero-3-PS(sodium salt)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
1,2-Dioleoyl-sn-glycero-3-PS(sodium salt)图片
CAS NO:90693-88-2
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
1,2-Dioleoyl-sn-glycero-3-PS（钠盐）是磷酸丝氨酸/磷脂酰丝氨酸的替代品。
Cas No.90693-88-2
别名1,2-二-(9Z-十八碳烯酰基)-sn-甘油-3-磷酰-L-丝氨酸钠盐
Canonical SMILESCCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(OC[C@H](N)C(O)=O)([O-])=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O.[Na+]
分子式C42H77NO10P.Na
分子量810
溶解度Chloroform: 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1,2-Dioleoyl-sn-glycero-3-PS (DOPS) is a phospholipid containing oleic acid at thesn-1 andsn-2 positions, respectively. Nanovesicles composed of DOPS and the lysosomal protein saposin C (SapC) are cytotoxic to SK-MEL-28 cellsin vitroand decrease tumor volume in a squamous cell carcinoma mouse xenograft model.[1] DOPS has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets.[2] [3]

Reference:
[1].Abu-Baker, S., Chu, Z., Stevens, A.M., et al.Cytotoxicity and selectivity in skin cancer by SapC-DOPS nanovesiclesJ. Cancer Ther.3(4)321-326(2012)
[2].Kucerka, N., Pencer, J., Sachs, J.N., et al.Curvature effect on the structure of phospholipid bilayersLangmuir23(3)1292-1299(2007)
[3].Richter, R.P., Maury, N., and Brisson, A.R.On the effect of the solid support on the interleaflet distribution of lipids in supported lipid bilayersLangmuir21(1)299-304(2005)