| CAS NO: | 214360-73-3 |
| 包装 | 价格(元) |
| 1 g | 电议 |
| 5 g | 电议 |
| 10 g | 电议 |
| Cas No. | 214360-73-3 |
| 别名 | 4-氨基苯硼酸频哪醇酯 |
| Canonical SMILES | NC(C=C1)=CC=C1B2OC(C)(C)C(C)(C)O2 |
| 分子式 | C12H18BNO2 |
| 分子量 | 219.1 |
| 溶解度 | DMF: 20mg/mL,DMF:PBS (pH 7.2) (1:5): 0.16mg/mL,DMSO: 10mg/mL,Ethanol: 3mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline is a heterocyclic building block.1,2It has been used in the synthesis of 3-aminoindazole-based multi-targeted receptor tyrosine kinase (RTK) inhibitors with anticancer activity and roscovitine derivatives that are dual inhibitors of cyclin-dependent kinases (CDKs) and casein kinase 1 (CK1). 1.Dai, Y., Hartandi, K., Ji, Z., et al.Discovery of N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-aminoindazole-based orally active multitargeted receptor tyrosine kinase inhibitorJ. Med. Chem.50(7)1584-1597(2007) 2.Paraiso, K.H.T., Haarberg, H.E., Wood, E., et al.The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanismsClin. Cancer Res.18(9)2502-2514(2012) |
m.cnreagent.com