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6-Chloro-2-fluoropurine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
6-Chloro-2-fluoropurine图片
CAS NO:1651-29-2
包装与价格：
包装价格(元)
250mg电议
1 g电议

产品介绍
A heterocyclic building block
Cas No.1651-29-2
别名2-氟-6-氯嘌呤
Canonical SMILESClC1=C2C(N=CN2)=NC(F)=N1
分子式C5H2ClFN4
分子量172.5
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV)in vitro.2

1.Wilson, S.C., Atrash, B., Barlow, C., et al.Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitorsBioorg. Med. Chem.19(22)6949-6965(2011) 2.Lee, K., Choi, Y., Gullen, E., et al.Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2',3'-unsaturated L-nucleosidesJ. Med. Chem.42(7)1320-1328(1999)