包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Canonical SMILES | OC(CC[C@H](NC(C)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)CCSC)=O)CCC(O)=O)=O)=O.CC(O)=O |
分子式 | C34H60N14O12S.XC2H4O2 |
分子量 | 889 |
溶解度 | PBS (pH 7.2): 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Acetyl hexapeptide-3 is a synthetic acetylated and amidated hexapeptide consisting of amino acid residues 12-17 of synaptosomal-associated protein 25 (SNAP-25).1It inhibits formation of the SNARE complexin vitroin a concentration-dependent manner. It also inhibits calcium-induced norepinephrine release in permeabilized chromaffin cells (IC50= 110 μM). Acetyl hexapeptide-3 (10% in an oil-and-water emulsion) inhibits decreases in type I collagen levels and skin thickness, as well as increases in type III collagen levels, in skin in a mouse model of subacute aging induced by D-galactose when administered topically.2 1.Blanes-Mira, C., Clemente, J., Jodas, G., et al.A synthetic hexapeptide (argireline) with antiwrinkle activityInt. J. Cosmet. Sci.24(5)303-310(2002) 2.Wang, Y., Wang, M., Xiao, X.S., et al.The anti-wrinkle efficacy of argirelineJ. Cosmet Laser Ther.15(4)237-241(2013) |