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Quercetin(hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Quercetin(hydrate)图片
CAS NO:849061-97-8
包装与价格:
包装价格(元)
5 g电议
10 g电议
50 g电议
100 g电议

产品介绍
A flavonoid with diverse biological activities
Cas No.849061-97-8
别名槲皮素二水合物
Canonical SMILESO=C(C(O)=C(C1=CC(O)=C(O)C=C1)O2)C3=C2C=C(O)C=C3O.O
分子式C15H10O7.XH2O
分子量302.2
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2)(1:4): 1 mg/ml,Ethanol: 2 mg/ml
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties.1,2,3Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy.2It reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1phase in an HL60 mouse xenograft model when administered at a dose of 120 mg/kg every four days.1Quercetin (30 µM) also inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-α, IL-1β, IL-6, and IL-8 induced by PMACI in HMC-1 cells.3

1.Calgarotto, A.K., Maso, V., Junior, G.C.F., et al.Antitumor activities of quercetin and green tea in xenografts of human leukemia HL60 cellsSci. Rep.8(1)3459(2018) 2.Yuan, Y., Ma, S., Qi, Y., et al.Quercetin inhibited cadmium-induced autophagy in the mouse kidney via inhibition of oxidative stressJ. Toxicol. Pathol.29(4)247-252(2016) 3.Park, H.H., Lee, S., Son, H.Y., et al.Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cellsArch. Pharm. Res.31(10)1303-1311(2008)