| CAS NO: | 51103-58-3 |
| 包装: | 1mg |
| 市场价: | 2797元 |
| Cas No. | 51103-58-3 |
| Canonical SMILES | C=C1CC[C@@]([C@](CC/C=C(C)/C)(C)[C@H](OC(C)=O)CC2)([H])[C@]2(C)[C@H]1CC3=C(O)C(C)=C(C)OC3=O |
| 分子式 | C29H42O5 |
| 分子量 | 470.6 |
| 溶解度 | Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Sesquicillin A is a fungal metabolite that has been found inAlbophoma.1It inhibits the growth ofA. salinabrine shrimp (MIC = 6.25 µg/ml). Sesquicillin is cytotoxic to Jurkat cells (IC50= 34 µM). It induces cell cycle arrest at the G1phase and inhibits proliferation of MCF-7 breast cancer cells when used at a concentration of 20 µg/ml.2 1.Uchida, R., Imasato, R., Yamaguchi, Y., et al.New sesquicillins, insecticidal antibiotics produced by Albophoma sp. FKI-1778J. Antibiot. (Tokyo)58(6)397-404(2005) 2.Jeong, H.W., Lee, H.J., Kho, Y.H., et al.Biological effects of G1 phase arrest compound, sesquicillin, in human breast cancer cell linesBioorg. Med. Chem.10(10)3129-3134(2002) |
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