| CAS NO: | 929095-23-8 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 929095-23-8 |
| Canonical SMILES | C[C@H](C1=C(C=CC=C1)Cl)OC(C=C2N3C4=CC(OC5CCN(CC5)C)=CC=C4N=C3)=C(S2)C(N)=O |
| 分子式 | C26H27ClN4O3S |
| 分子量 | 511 |
| 溶解度 | DMSO: 25 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | GSK579289A is an inhibitor of polo-like kinase 1 (Plk1; IC50= 2 nM).1It is selective for Plk1 over Plk3 (IC50= 630 nM). GSK579289A inhibits proliferation of HCT116 cells (IC50= 11 nM). 1.Rheault, T.R., Donaldson, K.H., Badiang-Alberti, J.G., et al.Heteroaryl-linked 5-(1H-benzimidazol-1-yl)-2-thiophenecarboxamides: Potent inhibitors of polo-like kinase 1 (PLK1) with improved drug-like propertiesBioorg. Med. Chem. Lett.20(15)4587-4592(2010) |
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