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IN04
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IN04图片
CAS NO:838816-57-2
规格:≥98%
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议
1g电议

产品介绍

IN04, also know as Methyl 3-(2-((5-(3,5-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)acetamido)benzoate, is a novel and potent inhibitor of Leucine rich repeat kinase 1 (LRRK1), suppressing osteoclasts (OC) function with no effect on OC formation. IN04 inhibits LRRK1 by binding to the active site of the kinase domain but not the ROC domain. LRRK1 plays a critical role in regulating OC function and peak bone mass. Therefore, LRRK1 is a novel drug target for alternative anti-resorptive drugs to treat osteoporosis and osteoporotic fractures.

纯度:≥98%

CAS:838816-57-2