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Corydalmine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Corydalmine图片
CAS NO:30413-84-4
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Corydalmine (L-Corydalmine) 抑制某些植物病原体的孢子萌发以及腐生真菌。Corydalmine 具有口服活性，可用于缓解疼痛的研究。Corydalmine 通过抑制 NF-κB 依赖性的 CXCL1/CXCR2 信号传导途径，可缓解 Vincristine 引起的神经性疼痛。
Cas No.30413-84-4
别名紫堇达明碱,L-Corydalmine; TLZ-16
分子式C20H23NO4
分子量341.4
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi[1]. Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity[2]. Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway[3].

Corydalmine (L-Corydalmine) is a potent analgesic agent, in cynomolgus monkey, beagle dog, rat and mouse liver microsomes[2].

[1]. S Ameer Basha, et al. Effect of 1-corydalmine, an Alkaloid Isolated From Corydalis Chaerophylla Roots on Spore Germination of Some Fungi. Mycobiology. 2007 Jun;35(2):69-71.
[2]. Xiange Tang, et al. In Vitro Metabolism of L-Corydalmine, a Potent Analgesic Drug, in Human, Cynomolgus Monkey, Beagle Dog, Rat and Mouse Liver Microsomes. J Pharm Biomed Anal. 2016 Sep 5;128:98-105.
[3]. Lin Zhou, et al. Levo-corydalmine Alleviates Vincristine-Induced Neuropathic Pain in Mice by Inhibiting an NF-kappa B-dependent CXCL1/CXCR2 Signaling Pathway. Neuropharmacology. 2018 Jun;135:34-47.