eCF309 是一种有效且高度选择性的 mTOR 抑制剂，具有非常低的脱靶活性（IC50 = 10-15 nM，在体外和细胞中）。
| Cas No. | 2001571-40-8 |
| Canonical SMILES | NC1=NC=NC2=C1C(C3=CC=C(OC(N)=N4)C4=C3)=NN2CC(OCC)OCC |
| 分子式 | C18H21N7O3 |
| 分子量 | 383.4 |
| 溶解度 | DMF: 1.6 mg/mL,DMSO: 2 mg/mL,DMSO:PBS (pH 7.2) (1:10): 0.09 mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | eCF309 is an ATP-competitive inhibitor of mTOR (IC50 = 15 nM in vitro and in cells) with >65-fold selectivity over other kinases, including PI3Ks. |
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