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2-Amino-5-bromo-6-chloropyrazine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2-Amino-5-bromo-6-chloropyrazine图片
CAS NO:173253-42-4
包装与价格:
包装价格(元)
250mg电议
500mg电议
1 g电议
5 g电议

产品介绍
A heterocyclic building block
Cas No.173253-42-4
别名2-氨基-5-溴-6-氯吡嗪
Canonical SMILESNC1=CN=C(Br)C(Cl)=N1
分子式C4H3BrClN3
分子量208.4
溶解度DMF: 25mg/mL,DMF:PBS (pH 7.2) (1:5): 0.16mg/mL,DMSO: 15mg/mL,Ethanol: 20mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Amino-5-bromo-6-chloropyrazine is a heterocyclic building block.1,2It has been used in the synthesis of Akt inhibitors.

1.Kettle, J.G., Brown, S., Crafter, C., et al.Diverse heterocyclic scaffolds as allosteric inhibitors of AKTJ. Med. Chem.55(3)1261-1273(2012) 2.Goel, R., Luxami, V., and Paul, K.Recent advances in development of imidazo[1,2-a]pyrazines: Synthesis, reactivity and their biological applicationsOrg. Biomol. Chem.13(12)3525-3555(2015)