| CAS NO: | 1246535-95-4 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 1246535-95-4 |
| 别名 | Desmethyl-SB2343 |
| Canonical SMILES | CC(C)N(C=N1)C2=C1C(C3=CN=C(N)N=C3)=NC(N4CCOCC4)=N2 |
| 分子式 | C16H20N8O |
| 分子量 | 340.4 |
| 溶解度 | Chloroform: 0.5mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | VS-5584 analog is a dual inhibitor of PI3Kα and mammalian target of rapamycin (mTOR; IC50s = 17 and 150 nM, respectively).1It is a desmethyl analog of the dual PI3K/mTOR inhibitor VS-5584 . 1.Poulsen, A., Nagaraj, H., Lee, A., et al.Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602J. Chem. Inf. Model54(11)3238-3250(2014) |
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