| CAS NO: | 40632-25-5 |
| 包装 | 价格(元) |
| 500 µg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 40632-25-5 |
| 别名 | 胞苷-D2,Cytosine β-D-riboside-d2; Cytosine-1-β-D-ribofuranoside-d2 |
| Canonical SMILES | O[C@H]1[C@@](N2C(N=C(C([2H])=C2[2H])N)=O)([H])O[C@@H]([C@H]1O)CO |
| 分子式 | C9H11D2N3O5 |
| 分子量 | 245.2 |
| 溶解度 | DMF: soluble,DMSO: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cytidine-d2is intended for use as an internal standard for the quantification of cytidine by GC- or LC-MS. Cytidine is a pyrimidine nucleoside composed of ribose and a cytosine base.1It forms complementary base pairs with the purine nucleoside guanosine in DNA and RNA. Cytidine is a precursor of uridine and can also be phosphorylated by uridine-cytidine kinase to form cytidine 5’-monophosphate .2,1It rescues inhibition of proliferation induced by knockdown of CTP synthase 1 in T cells when used at a concentration of 200 µM.3 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Nucleotide biosynthesisBiochemistry(2002) 2.Chabner, B.A., Johns, D.G., Coleman, C.N., et al.Purification and properties of cytidine deaminase from normal and leukemic granulocytesJ. Clin. Invest.53(3)922-931(1974) 3.Martin, E., Palmic, N., Sanquer, S., et al.CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferationNature510(7504)288-292(2014) |
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