| CAS NO: | 6379-56-2 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 6379-56-2 |
| 别名 | 匀霉素 |
| Canonical SMILES | O[C@H]1[C@@]2([H])[C@@](OCO2)([H])[C@@H]([C@H]([C@H]1NC(/C(C)=C/C3=CC(O)=C(C=C3)O[C@H]4[C@@H](O)[C@H](O)[C@@H](C(C)=O)O4)=O)O)O |
| 分子式 | C23H29NO12 |
| 分子量 | 511.5 |
| 溶解度 | DMF: 16 mg/mL,DMSO: 10 mg/mL,Ethanol: 12 mg/mL,PBS (pH 7.2): 10 mg/mL |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Hygromycin A is an antibiotic originally isolated fromS. hygroscopicus.1It is active against numerous spirochete bacteria, includingT. pallidum,L. biflexa, and four strains ofB. burgdorferi(MICs = 0.03-4 µg/ml for all). Hygromycin A binds to the peptidyl transferase center (PTC) in the 70S ribosomal subunit to inhibit protein synthesis. It completely eliminates bacterial infection in skin biopsies fromB. burgdorferi-infected mice in a model of acute Lyme disease when administered at doses ranging from 50 to 250 mg/kg twice per day. 1.Leimer, N., Wu, X., Imai, Y., et al.A selective antibiotic for Lyme diseaseCell184(21)5405-5418.e5416(2021) |
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