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NITD-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NITD-2图片
CAS NO:1197896-79-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
NITD-2 是登革病毒 (DENV) 聚合酶抑制剂,抑制DENV RdRp 蛋白介导的 RNA 延伸。NITD-2 的细胞膜透过性较差。
Cas No.1197896-79-9
分子式C23H19N3O4S
分子量433.48
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly[1].

NITD-2 inhibits de novo RNA synthesis[1].NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration[1].

[1]. Pornwaratt Niyomrattanakit, et al. Inhibition of dengue virus polymerase by blocking of the RNA tunnel. J Virol. 2010 Jun;84(11):5678-86.