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IRAK-4 protein kinase inhibitor 2
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
IRAK-4 protein kinase inhibitor 2图片
CAS NO:301675-24-1
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议

产品介绍
IRAK-4 protein kinase inhibitor 2 (compound 1) 是一种有效的白介素 1 (IL-1) 受体相关激酶 4 (IRAK-4) 抑制剂，IC50 值为 4 μM。IRAK-4 protein kinase inhibitor 2 可用于研究与炎症和免疫相关的疾病。
Cas No.301675-24-1
别名N-(-1H-苯并[D]咪唑-2-基)-3-硝基苯甲酰胺
分子式C14H10N4O3
分子量282.25
溶解度DMSO : 10 mg/mL (35.43 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

IRAK-4 protein kinase inhibitor 2 (compound 1) is a potent inhibitor of interleukin-1 (IL-1) receptor-associated kinase-4 (IRAK-4), with an IC50 of 4 μM. IRAK-4 protein kinase inhibitor 2 can be used for the research of inflammatory and immune-related conditions or disorders[1].

IRAK-4 protein kinase inhibitor 2 (compound 1) also inhibits IRAK-1, with an IC50 of<10 μM[1].

[1]. Powers JP, et, al. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.