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(S)-p38 MAPK Inhibitor III
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(S)-p38 MAPK Inhibitor III图片
CAS NO:581098-48-8
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议
10mg电议

产品介绍
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro).
Cas No.581098-48-8
Canonical SMILESFC1=CC=C(C2=C(C3=CC=NC(N[C@@H](C)C4=CC=CC=C4)=C3)N=C(SC)N2)C=C1
分子式C23H21FN4S
分子量404.5
溶解度DMF: 20 mg/mL,DMSO: 12 mg/mL,Ethanol: 30 mg/mL,Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 µM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 µM, respectively).