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Ganglioside GQ1b Mixture(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ganglioside GQ1b Mixture(sodium salt)图片
CAS NO:68652-37-9
包装与价格:
包装价格(元)
100μg电议
500μg电议

产品介绍
Cas No.68652-37-9
别名神经节苷脂GQ1B四钠盐
Canonical SMILESCCCCCCCCCCCCC/C=C/[C@]([H])([C@](NC(CCCCCCCCCCCCCCCCC)=O)([H])CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O[C@@]3(C([O-])=O)O[C@H]([C@@H]([C@H](C3)O)NC(C)=O)[C@@H](O)[C@H](O[C@@]4(C([O-])=O)O[C@H]([C@@H]([C@H](C4)O)N
分子式C106H178N6O55•4Na (for Sphingosine C18:1)
分子量2508.5
溶解度Chloroform:Methanol (2:1): Soluble,Water: Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO human neuroblastoma cells when used at a concentration of 5 nM. Ganglioside GQ1b promotes differentiation of murine embryonic stem cells (mESCs) to neuronal precursor and glial cells via activation of the ERK1/2 pathway. It also induces differentiation of murine keratinocytes through phosphoinositide turnover. Ganglioside GQ1b mixture contains ganglioside GQ1b molecular species with C18:1 and C20:1 sphingoid backbones.