| CAS NO: | 64564-03-0 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 64564-03-0 |
| 别名 | Gpp(NH)p lithium |
| 化学名 | 5’-guanylic acid, monoanhydride with imidodiphosphoric acid, tetralithium salt |
| Canonical SMILES | O[C@H]1[C@H](N2C=NC3=C2N=C(N)NC3=O)O[C@H](COP(OP(NP([O-])([O-])=O)([O-])=O)([O-])=O)[C@H]1O.[Li+].[Li+].[Li+].[Li+] |
| 分子式 | C10H13N6O13P3o 4Li |
| 分子量 | 545.9 |
| 溶解度 | 10mg/mL in PBS, pH7.2 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Guanylyl imidodiphosphate is a nonhydrolyzable analog of GTP that can bind to and irreversibly activate G proteins in the presence of Mg2+.[1] This nucleotide is a potent stimulator of adenylate cyclase.[2] Guanylyl imidodiphosphate is used in studies of protein synthesis since the process of GTP binding, hydrolysis, and release is essential for the initiation of protein translocation across the endoplasmic reticulum.[3] Reference: [1]. Terry, B.J., and Purich, D.L. Assembly and disassembly properties of microtubules formed in the presence of GTP, 5'-guanylyl imidodiphosphate, and 5'-guanylyl methylenediphosphate. The Journal of Biological Chemisty 255(21), 10532-10536 (1980). [2]. Lefkowitz, R.J., and Caron, M.G. Characteristics of 5'-guanylyl imidodiphosphate-activated adenylate cyclase. The Journal of Biological Chemisty 250(12), 4418-4422 (1975). [3]. Rapoport, T.A. Transport of proteins across the endoplasmic reticulum membrane. Science 258(5084), 931-936 (1992). |
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