| CAS NO: | 40632-23-3 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 40632-23-3 |
| 别名 | 2'-脱氧尿苷-5,6-D2 |
| Canonical SMILES | OC[C@H]1O[C@](N2C(NC(C([2H])=C2[2H])=O)=O)([H])C[C@@H]1O |
| 分子式 | C9H10D2N2O5 |
| 分子量 | 230.2 |
| 溶解度 | DMF: 16 mg/mL,DMSO: 10mg/mL,Ethanol: slightly soluble,PBS (pH 7.2): 5mg/mL |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 2’-Deoxyuridine-d2is intended for use as an internal standard for the quantification of 2’-deoxyuridine by GC- or LC-MS. 2’-Deoxyuridine is a pyrimidine nucleoside composed of the pyrimidine base uracil attached to the sugar deoxyribose.1It has been used as a precursor in the synthesis of antiviral deoxyuridine derivatives, including idoxuridine .2,3Formulations containing 2’-deoxyuridine have been used in the deoxyuridine suppression test to identify vitamin B12 and/or folate deficiency and in the diagnosis of megaloblastic anemias. 1.MartÍ, R., LÓpez, L.C., and Hirano, M.Assessment of thymidine phosphorylase function: Measurement of plasma thymidine (and deoxyuridine) and thymidine phosphorylase activityMethods Mol. Biol.837121-133(2012) 2.Prusoff, W.H.Synthesis and biological activities of iododeoxyuridine, an analog of thymidineBiochim. Biophys. Acta.32(1)295-296(1959) 3.Bergstrom, D.E., and Ogawa, M.K.C-5 substituted pyrimidine nucleosides. 2. Synthesis via olefin coupling to organopalladium intermediates derived from uridine to 2’-deoxyuridineJ. Am. Chem. Soc.100(26)8106-8112(1978) |
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