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Rabeprazole sulfone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rabeprazole sulfone图片
CAS NO:117976-47-3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A metabolite of rabeprazole
Cas No.117976-47-3
别名雷贝拉唑杂质E
Canonical SMILESCC1=C(CS(C2=NC3=C(C=CC=C3)N2[H])(=O)=O)N=CC=C1OCCCOC
分子式C18H21N3O4S
分子量375.4
溶解度Acetone: slightly,Methanol: slightly
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Rabeprazole sulfone is a metabolite of the proton pump inhibitor rabeprazole .1It is formed from rabeprazole by the cytochrome P450 (CYP) isoform CYP3A. Rabeprazole sulfone has also been found as an impurity in bulk preparations of rabeprazole.2

1.VandenBranden, M., Ring, B.J., Binkley, S.N., et al.Interaction of human liver cytochromes P450 in vitro with LY307640, a gastric proton pump inhibitorPharmacogenetics6(1)81-91(1996) 2.Reddy, G.M., Bhaskar, B.V., Reddy, P.P., et al.Identification and characterization of potential impurities of rabeprazole sodiumJ. Pharm. Biomed. Anal.43(4)1262-1269(2007)