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Milvexian
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Milvexian图片
CAS NO:1802425-99-5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Milvexian (BMS-986177) 是一种口服生物利用度高、可逆、直接的人和兔因子 (FXIa) 抑制剂,其 Ki 值分别为 0.11 nM 和 0.38 nM。
Cas No.1802425-99-5
别名BMS-986177; JNJ-70033093
分子式C28H23Cl2F2N9O2
分子量626.44
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Milvexian (BMS-986177), an effective antithrombotic agent, is an orally-bioavailable, reversible and direct inhibitor of human and rabbit factor XIa (FXIa) with Ki of 0.11, and 0.38 nM, respectively[1].

[1]. Wong P, et al. Small-Molecule Factor XIa Inhibitor, BMS-986177/JNJ-70033093, Prevents and Treats Arterial Thrombosis in Rabbits at Doses that Preserve Hemostasis [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1).