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rac-Hesperetin-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
rac-Hesperetin-d3图片
CAS NO:1346605-26-2
包装:1mg
市场价:4130元

产品介绍
An internal standard for the quantification of hesperetin
Cas No.1346605-26-2
别名三氘代橙皮素
Canonical SMILESOC1=C(OC([2H])([2H])[2H])C=CC(C2CC(C3=C(O)C=C(O)C=C3O2)=O)=C1
分子式C16H11D3O6
分子量305.3
溶解度Methanol: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

rac-Hesperetin-d3is intended for use as an internal standard for the quantification of hesperetin by GC- or LC-MS.rac-Hesperetin is a racemic mixture of the flavanones (S)-hesperetin and (R)-hesperetin.rac-Hesperetin (1 mM) inhibits heat-induced advanced glycation end product formation between BSA and glucose by 56.7%.1It also inhibits α-glucosidase and protein tyrosine phosphatase 1B (PTP1B; IC50s = 15.28 and 20.16 µM, respectively).2rac-Hesperetin (100 µM) protects against hydrogen peroxide-induced cytotoxicity in MIN6 pancreatic beta cells by 72.27%.

1.Li, D., Mitsuhashi, S., and Ubukata, M.Protective effects of hesperidin derivatives and their stereoisomers against advanced glycation end-products formationPharm. Biol.50(12)1531-1535(2012) 2.Xu, J., Wang, X., Yue, J., et al.Polyphenols from acorn leaves (Quercus liaotungensis) protect pancreatic beta cells and their inhibitory activity against α-glucosidase and protein tyrosine phosphatase 1BMolecules23(9)2167(2018)