| CAS NO: | 402491-35-4 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| Cas No. | 402491-35-4 |
| 别名 | 2'-脱氧腺苷-5'-二磷酸三钠 |
| Canonical SMILES | NC1=NC=NC2=C1N=CN2[C@@]3([H])C[C@H](O)[C@@H](COP(OP([O-])([O-])=O)([O-])=O)O3.[Na+].[Na+].[Na+] |
| 分子式 | C10H12N5O9P2 • 3Na |
| 分子量 | 477.2 |
| 溶解度 | PBS (pH 7.2): 10mg/mL |
| 储存条件 | -20буC |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 2’-Deoxyadenosine-5’-diphosphate (dADP) is a purine nucleotide diphosphate.1It inhibits the polymerization of ADP and CDP byE. coliorP. fluorescenspolynucleotide phosphorylase when used at a concentration of 0.23 mM.2dADP levels are increased in erythrocytes isolated from patients with adenosine deaminase (ADA) deficiency, an inborn error of metabolism characterized by severe combined immunodeficiency (SCID).3 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Nucleotide biosynthesisBiochemistry(2002) 2.Lucas-Lenard, J.M., and Cohen, S.S.The inhibition of polynucleotide phosphorylase by certain substrate analoguesBiochim. Biophys. Acta123(3)471-477(1966) 3.Coleman, M.S., Donofrio, J., Hutton, J.J., et al.Identification and quantitation of adenine deoxynucleotides in erythrocytes of a patient with adenosine deaminase deficiency and severe combined immunodeficiencyJ. Biol. Chem.253(5)1619-1626(1978) |
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