| 包装: | 5mg |
| 市场价: | 4336元 |
| Canonical SMILES | O=C(NC)CN(N=C1)C=C1C(C=C2)=CC3=C2C(N4)(CC3F)C(N(CC(N(CC5=CC=C(F)C=C5)C(C)C(F)(F)F)=O)C4=O)=O |
| 分子式 | C29H27F5N6O4 |
| 分子量 | 618.55 |
| 溶解度 | DMSO|61.85|100| |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Potent p300/CBP inhibitor. Inhibits p300-mediated H3K9 acetylation (IC50 = 33 nM). Inhibits cytotoxicity of DUX4 and overexpression of DUX4 target genes in vitro. Also impairs DUX4-mediated transcription in an animal model of facioscapulohumeral muscular dystrophy (FSHD). |
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