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FTX-6058
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FTX-6058图片
CAS NO:2490676-18-9
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
FTX-6058 ((S)-FTX-6058) 是一种有效的、具有口服活性的胚胎外胚层发育 (EED) 抑制剂。
Cas No.2490676-18-9
别名(S)-FTX-6058
分子式C22H18FN5O2
分子量403.41
溶解度DMSO : 125 mg/mL (309.86 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

FTX-6058 is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 can induce HbF protein expression in cell and murine models. FTX-6058 can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2].

FTX-6058 inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models[2].

[1]. Boerner LK. Virtual meeting delivers first time drug structures. April 12, 2021.
[2]. Fulcrum Therapeutics Presents Published Structure of Investigational Small Molecule FTX-6058 at the American Chemical Society (ACS) Spring 2021 Virtual Conference.