| CAS NO: | 125354-16-7 |
| 包装 | 价格(元) |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 125354-16-7 |
| 别名 | 多西他赛,10-Acetyl docetaxel; PNU-101383 |
| Canonical SMILES | C[C@]1(C([C@@H](C2=C(C)[C@@H](OC([C@H](O)[C@@H](NC(OC(C)(C)C)=O)C3=CC=CC=C3)=O)C[C@]4(O)C2(C)C)OC(C)=O)=O)[C@@]([C@@H]4OC(C5=CC=CC=C5)=O)([H])[C@@]([C@@]6([H])C[C@@H]1O)(CO6)OC(C)=O |
| 分子式 | C45H55NO15 |
| 分子量 | 849.9 |
| 溶解度 | DMF: 2 mg/ml,DMSO: 3 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): insol |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 10-acetyl Docetaxel is a derivative of paclitaxel and an inhibitor of microtubule depolymerization.1It inhibits calcium-induced depolymerization of calf brain microtubule protein (MTP) in a cell-free assay when used at 20 µM. 10-acetyl Docetaxel is cytotoxic to J774.2 cells (EC50= 0.05 µM). 1.Swindell, C.S., Heerding, J.M., Krauss, N.E., et al.Characterization of the taxol structure-activity profile for the locus of the A-ring side chainBioorg. Med. Chem. Lett.4(12)1531-1536(1994) |
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