| CAS NO: | 1331888-08-4 |
| 包装: | 1mg |
| 市场价: | 8100元 |
| Cas No. | 1331888-08-4 |
| 别名 | 精氨酸杂质,Symmetric dimethylarginine-d6; NG,NG'-Dimethyl-L-arginine-d6 |
| 分子式 | C8H12D6N4O2 |
| 分子量 | 208.29 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SDMA-d6 (Symmetric dimethylarginine-d6) is the deuterium labeled SDMA. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity[1][2]. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Bode-BÖger SM,et al. Symmetrical dimethylarginine: a new combined parameter for renal function and extent ofcoronary artery disease. |
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