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Albendazole sulfone-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Albendazole sulfone-d3图片
CAS NO:1448345-60-5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
An internal standard for the quantification of albendazole sulfone
Cas No.1448345-60-5
别名阿苯哒唑砜-D3
Canonical SMILESCCCS(=O)(C1=CC=C(N=C(N2)NC(OC([2H])([2H])[2H])=O)C2=C1)=O
分子式C12H12D3N3O4S
分子量300.3
溶解度DMF: 1 mg/ml,DMSO: slightly,Ethanol: insol,PBS (pH 7.2): insol
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Albendazole sulfone-d3is intended for use as an internal standard for the quantification of albendazole sulfone by GC- or LC-MS. Albendazole sulfone is an active metabolite of the benzimidazole anthelmintic albendazole .1,2It inhibits spore formation ofE. hellem, E. cuniculi, andE. intestinalis in vitro(IC90s =<0.0001,<0.001, and<0.1 µg/ml, respectively).2

1.BaliharovÁ, V., VelÍk, J., FimanovÁ, K., et al.Inhibitory effect of albendazole and its metabolites on cytochromes P450 activities in rat and mouflon in vitroPharmacol. Rep.5797-106(2005) 2.Ridoux, O., and Drancourt, M.In vitro susceptibilities of the microsporidia Encephalitozoon cuniculi, Encephalitozoon hellem, and Encephalitozoon intestinalis to albendazole and its sulfoxide and sulfone metabolitesAntimicrob. Agents and Chemother.42(12)3301-3303(1998)