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3-Methoxytyrosine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3-Methoxytyrosine图片
CAS NO:7636-26-2
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍
An active metabolite of L-DOPA
Cas No.7636-26-2
别名2-氨基-3-(4-羟基-3-甲氧基苯基)丙酸
Canonical SMILESO=C(C(CC1=CC=C(C(OC)=C1)O)N)O
分子式C10H13NO4
分子量211.2
溶解度Acetonitrile: Slightly soluble,Chloroform: Slightly soluble,DMF: Slightly soluble,DMSO: Slightly soluble,PBS (pH 7.2): Slightly soluble,Water: Slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3-Methoxytyrosine is an active metabolite of L-DOPA .1It is formed from L-DOPAviaO-methylation by catechol-O-methyltransferase (COMT). 3-Methoxytyrosine (10 and 100 µM) inhibits L-DOPA-induced neuroprotection in primary rat mesencephalic dopaminergic neurons.2

1.Miller, J.W., Shukitt-Hale, B., Villalobos-Molina, R., et al.Effect of ?-Dopa and the catechol-O-methyltransferase inhibitor Ro 41-0960 on sulfur amino acid metabolites in ratsClin. Neuropharmacol.20(1)55-66(1997) 2.Asanuma, M., and Miyazaki, I.3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of ?-DOPABMC Neurosci.17(1)52(2016)