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Desmethyl Sibutramine(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Desmethyl Sibutramine(hydrochloride)图片
CAS NO:84467-94-7
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
An active metabolite of sibutramine
Cas No.84467-94-7
别名N-去甲盐酸西布曲明,N-Desmethylsibutramine hydrochloride
Canonical SMILESClC1=CC=C(C2(C(CC(C)C)NC)CCC2)C=C1.Cl
分子式C16H24ClN • HCl
分子量302.3
溶解度Water: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Desmethyl sibutramine is an active metabolite of sibutramine.1It prevents reserpine-induced ptosis in rats (ED50= 4.2 mg/kg) and decreases immobility in the Porsolt learned helplessness test in mice when administered at a dose of 10 mg/kg.

1.Luscombe, G.P., Hopcroft, R.H., Tomas, P.C., et al.The contribution of metabolites to the rapid and potent down-regulation of rat cortical β-adrenoceptors by the putative antidepressant sibutramine hydrochlorideNeuropharmacology28(2)129-134(1989)