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Dofetilide N-oxide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dofetilide N-oxide图片
CAS NO:144449-71-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Dofetilide N-oxide (UK-116856) 是 Dofetilide 的代谢物。
Cas No.144449-71-8
别名多非利特氮氧化物,UK-116856
Canonical SMILESO=N(CCOC1=CC=C(NS(=O)(C)=O)C=C1)(CCC2=CC=C(NS(=O)(C)=O)C=C2)C
分子式C19H27N3O6S2
分子量457.6
溶解度DMF: insol,DMSO: 1 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
储存条件-20буC
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dofetilide N-oxide is a metabolite of the antiarrhythmic agent dofetilide .1It prolongs intracellular action potential duration in isolated guinea pig papillary muscle, as a measure of antiarrhythmic activity, less potently than dofetilide.

1.Walker, D.K., Alabaster, C.T., Congrave, G.S., et al.Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo dataDrug Metab. Dispos.24(4)447-455(1996)