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(S,S)-TAPI-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(S,S)-TAPI-1图片
CAS NO:171235-71-5
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
(S,S)-TAPI-1 是 TAPI-1 的异构体。TAPI-1是一种 TACE (ADAM17) 抑制剂,可阻止多种细胞表面蛋白脱落。TAPI-1 也是金属蛋白酶 (MMP) 抑制剂。
Cas No.171235-71-5
分子式C26H37N5O5
分子量499.6
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(S,S)-TAPI-1 is an isomer of TAPI-1. TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins. TAPI-1 is also a metalloproteinase (MMP) inhibitor[1][2].

[1]. Bae EH, et al. Tumor necrosis factor α-converting enzyme inhibitor attenuates lipopolysaccharide-induced reactive oxygen species and mitogen-activated protein kinase expression in human renal proximal tubule epithelial cells. Korean J Physiol Pharmacol. 2018 Mar;22(2):135-143.
[2]. Moss ML, et al. Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation. Mediators Inflamm. 2017;2017:9673537.