Cas No. | 67910-12-7 |
别名 | 11-脱氢凝血烷B2 |
化学名 | 9α,15S-dihydroxy-11-oxothromba-5Z,13E-dien-1-oic acid |
Canonical SMILES | CCCCC[C@H](O)/C=C/[C@H]1OC(C[C@H](O)[C@@H]1C/C=C\CCCC(O)=O)=O |
分子式 | C20H32O6 |
分子量 | 368.5 |
溶解度 | DMF: >50 mg/ml (from TXB2),DMSO: >25 mg/ml (from TXB2),Ethanol: >100 mg/ml (from TXB2),PBS pH 7.2: >100 µ g/ml (from TXB2) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 11-dehydro TXB2 is one of the main plasma metabolites of TXB2 and can be used as a marker for in vivo TXA2 synthesis. The mean plasma level in human males is 0.9-4.3 pg/ml and the half life is 45-60 minutes. Urinary concentrations of 11-dehydro TXB2 are approximately 30-70 ng/mmol creatinine. |