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Forphenicine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Forphenicine图片
CAS NO:57784-96-0
包装:1mg
市场价:7031元

产品介绍
A bacterial metabolite and an inhibitor of alkaline phosphatase
Cas No.57784-96-0
Canonical SMILESOC([C@H](C1=CC(O)=C(C=C1)C=O)N)=O
分子式C9H9NO4
分子量195.2
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Forphenicine is a bacterial metabolite that has been found inS. fulvoviridisand an inhibitor of alkaline phosphatase (IC50= 0.036 µg/ml for the chicken intestine enzyme).1It inhibits the growth of HL-60 leukemia cells when used at a concentration of 10 µM.2Forphenicine (50 and 500 µg/animal) increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).3

1.Aoyagi, T., Yamamoto, T., Kojiri, K., et al.Forphenicine, and inhibitor of alkaline phosphatase produced by actinomycetesJ. Antibiot. (Tokyo)31(3)244-246(1978) 2.Miura, K., Sawa, T., Takeuchi, T., et al.Effects of enzyme inhibitors in inhibiting the growth and inducing the differentiation of human promyelocytic leukemia cells, HL-60J Antibiot (Tokyo)39(5)734-735(1986) 3.Aoyagi, T., Wada, T., Nagai, M., et al.Low-molecular-weight enzyme inhibitors suppress the development of experimental allergic encephalomyelitisExperientia40(12)1405-1407(1984)