Dimethyl L-glutamate

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

6525-53-7

包装与价格：

包装	价格(元)
10g	电议
100g	电议

产品介绍

Dimethyl L-glutamate (Dimethyl glutamate), 一种可透膜的谷氨酸类似物，可刺激葡萄糖诱导的胰岛素 (insulin) 释放。Dimethyl L-glutamate 抑制 KATP 通道的活性。Dimethyl L-glutamate 抑制 E. gracilis 生长并导致细胞异常分裂。Dimethyl L-glutamate 可用于糖尿病、葡萄糖转运、磷酸化和进一步代谢的研究。

Cas No.	6525-53-7
别名	Dimethyl glutamate
分子式	C₇H₁₃NO₄
分子量	175.18
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulateinsulinrelease induced by Glucose. Dimethyl L-glutamate suppresses theK_ATPchannel activities. Dimethyl L-glutamate inhibitsE. gracilisgrowth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism^[1]^[2]^[3]^[4]. [1]. J Cancelas, et al. Potentiation by glutamic acid dimethyl ester of GLP-1 insulinotropic action in fed anaesthetized rats. Int J Mol Med. 2001 Nov;8(5):531-2. [2]. Sener A, et al. Insulinotropic action of glutamic acid dimethyl ester. American Journal of Physiology-Endocrinology and Metabolism, 1994, 267(4): E573-E584. [3]. I S Owens, et al. Induction of abnormal cell division in Euglena gracilis by glutamic diethyl ester. J Protozool. 1969 May;16(2):211-5. [4]. Hidenori Katsuta, et al. Insulinotropic action of glutamate is dependent on the inhibition of ATP-sensitive potassium channel activities in MIN 6 beta cells. Biochem Biophys Res Commun. 2003 Nov 21;311(3):660-4.