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1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC图片
CAS NO:162440-05-3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A lysophospholipid
Cas No.162440-05-3
Canonical SMILESO[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O
分子式C30H50NO7P
分子量567.7
溶解度Chloroform: 10 mg/ml
储存条件Store at -80°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC is a lysophospholipid containing docosahexaenoic acid at thesn-1 position that has been found in shark liver extract.11-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC decreases LPS-induced increases in TNF-α and IL-6 levels in RAW 264.7 cells in a concentration-dependent manner.2It decreases LPS-induced production of nitric oxide (NO) in RAW 264.7 cells when used at concentrations ranging from 12 to 200 µM. 1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC (15-500 µg/kg) inhibits plasma leakage into the peritoneum in a mouse model of peritonitis induced by zymosan A .

1.Chen, S., and Li, K.W.Mass spectrometric identification of molecular species of phosphatidylcholine and lysophosphatidylcholine extracted from shark liverJ. Agric. Food Chem.55(23)9670-9677(2007) 2.Huang, L.S., Hung, N.D., Sok, D.-E., et al.Lysophosphatidylcholine containing docosahexaenoic acid at the sn-1 position is anti-inflammatoryLipids45(3)225-236(2010)