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Fluocortolone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fluocortolone图片
CAS NO:152-97-6
包装:5mg
市场价:10150元

产品介绍
A glucocorticoid
Cas No.152-97-6
别名氟可龙
Canonical SMILESC[C@@]12[C@](C[C@H]([C@@H]2C(CO)=O)C)([H])[C@@]3([H])[C@@]([C@H](C1)O)([H])[C@@]4(C([C@H](C3)F)=CC(C=C4)=O)C
分子式C22H29FO4
分子量376.5
溶解度Chloroform: soluble,Methanol: soluble,Water: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fluocortolone is a glucocorticoid.1,2It inhibits progesterone 3α-hydroxysteroid dehydrogenase in rat cortical homogenates (IC50= 40 µM).1Fluocortolone (3, 6, and 12 mg/kg) decreases adjuvant-induced paw edema in rats.2

1.StÜrenburg, H.J., Fries, U., and Kunze, K.Glucocorticoids and anabolic/androgenic steroids inhibit the synthesis of GABAergic steroids in rat cortexNeuropsychobiology35(3)143-146(1997) 2.Bhargava, A.S.Effect of anti-inflammatory agents on adjuvant-induced edema modified for primary testPharmacol. Res. Commun.3(1)83-91(1971)