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Fulvestrant 9-sulfone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fulvestrant 9-sulfone图片
CAS NO:98008-06-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
An estrogen receptor antagonist and a derivative of fulvestrant
Cas No.98008-06-1
别名氟维司群-9-砜
Canonical SMILESOC1=CC=C2C(C[C@@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)(=O)=O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4O)=C1
分子式C32H47F5O4S
分子量622.8
溶解度DMSO: slightly soluble,Methanol: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fulvestrant 9-sulfone is an estrogen receptor antagonist and a derivative of the selective estrogen receptor degrader (SERD) fulvestrant .1It binds to estrogen receptor α (ERα) and ERβ and inhibits estrogen-induced gene expression in a reporter assay in Ishikawa endometrial cells expressing an estrogen response element (ERE) reporter when used at concentrations ranging from 0.1 to 100 µM.

1.Nuttall, M.E., Pendrak, I., Emery, J.G., et al.Antagonism of oestrogen action in human breast and endometrial cells in vitro: Potential novel antitumour agentsCancer Chemother. Pharmacol.47(5)437-443(2001)