| CAS NO: | 516-42-7 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 516-42-7 |
| 别名 | Β-皮甾酮四醇 |
| Canonical SMILES | C[C@@]12[C@](CC[C@]2(O)[C@@H](O)CO)([H])[C@@]3([H])[C@@](C(C1)=O)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C |
| 分子式 | C21H34O5 |
| 分子量 | 366.5 |
| 溶解度 | DMSO: soluble,Ethanol: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | α-Cortolone is a metabolite of the glucocorticoid cortisol .1It is formed from cortisol by 20α-hydroxysteroid dehydrogenase (20α-HSD)viaa tetrahydrocortisone intermediate. Urinary levels of α-cortolone are decreased in patients with severe anorexia nervosa and in postmenopausal women with endometrial adenocarcinoma compared to postmenopausal women without endometrial adenocarcinoma.2,3 1.Espiard, S., McQueen, J., Sherlock, M., et al.Improved urinary cortisol metabolome in Addison disease: A prospective trial of dual-release hydrocortisoneJ. Clin. Endocrinol. Metab.106(3)814-825(2021) 2.Wassif, W.S., McLoughlin, D.M., Vincent, R.P., et al.Steroid metabolism and excretion in severe anorexia nervosa: Effects of refeedingAm. J. Clin. Nutr.93(5)911-917(2011) 3.Bufa, A., BÍrÓ, I., PoÓr, V., et al.Altered urinary profiles of endogenous steroids in postmenopausal women with adenocarcinoma endometriiGynecol. Endocrinol.26(1)10-15(2010) |
m.cnreagent.com