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Solanidine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Solanidine图片
CAS NO:80-78-4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Solanidine 是一种胆甾烷生物碱,从几种马铃薯物种中分离出来,包括 Solanum demissum、Solanum acaule 和 Solanum tuberosum。茄尼定能抑制增殖并表现出明显的抗肿瘤作用。
Cas No.80-78-4
别名茄次碱
Canonical SMILESC[C@@]12[C@]3([H])[C@@](C[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)O)=CC4)C)([H])CC2)([H])N6[C@@](CC[C@@H](C6)C)([H])[C@H]3C
分子式C27H43NO
分子量397.6
溶解度DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件-20буC
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Solanidine is a steroidal glycoalkaloid metabolite that has been found in potato (S. tuberosum) and has anticancer and teratogenic activities.1,2,3It inhibits the growth of HT-29 colon and HepG2 liver cancer cells by 80.9 and 82.2%, respectively, when used at a concentration of 100 μg/ml.2Solanidine (176 mg/kg) is teratogenic to hamster embryos when administered to pregnant dams on day eight of gestation.3

1.Nikolic, N.C., and Stankovic, M.Z.Solanidine hydrolytic extraction and separation from the potato (Solanum tuberosum L.) vines by using solid-liquid-liquid systemsJ. Agric. Food Chem.51(7)1845-1849(2003) 2.Lee, K.-R., Kozukue, N., Han, J.-S., et al.Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cellsJ. Agric. Food Chem.52(10)2832-2839(2004) 3.Gaffield, W., and Keeler, R.F.Implication of C-5, C-6 unsaturation as a key structural factor in steroidal alkaloid-induced mammalian teratogenesisExperientia49(10)922-924(1993)