您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > PEG diamine
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
PEG diamine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PEG diamine图片
CAS NO:24991-53-5
包装与价格:
包装价格(元)
1 g电议
5 g电议

产品介绍
A PEGylated building block
Cas No.24991-53-5
别名聚氧乙烯双胺
Canonical SMILESNCCOCCOCCN
分子式(C2H4O)nC4H12N2O
分子量0
溶解度DMF: 33 mg/ml,DMSO: 33 mg/ml,Ethanol: 33 mg/ml,PBS (pH 7.2): 5 mg/ml
储存条件-20буC
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

PEG diamine is a PEGylated building block.1,2It has been used as a linker to conjugate folic acid to 1,2-distearoyl-rac-glycero-PE (1,2-DSPE) as a component in the formation of doxorubicin-containing liposomes with anticancer activity.1PEG diamine has also been conjugated to oleanolic acid , which improves oleanolic acid-induced inhibition of cell proliferation by 677-fold in HepG2 hepatocellular carcinoma cells.2

1.Lee, R.J., and Low, P.S.Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitroBiochim. Biophys. Acta1233(2)134-144(1995) 2.Jannus, F., Medina-O’Donnell, M., Rivas, F., et al.A diamine-PEGylated oleanolic acid derivative induced efficient apoptosis through a death receptor and mitochondrial apoptotic pathway in HepG2 human hepatoma cellsBiomolecules10(10)1375(2020)