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M4 mAChR agonist-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
M4 mAChR agonist-1图片
CAS NO:785705-53-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
M4 mAChR agonist-1 (compound 10a) 是一种有效的 M4 mAChR 激动剂,对人 M4 的 IC50 >10 μM。
Cas No.785705-53-5
分子式C14H18N4OS
分子量290.38
溶解度DMSO : 20 mg/mL (68.88 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 70°C)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4[1].

[1]. Wood MR, et al. Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core. Bioorg Med Chem Lett. 2016;26(13):3029-3033.