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4-methoxy Estrone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
4-methoxy Estrone图片
CAS NO:58562-33-7
包装与价格：
包装价格(元)
500 µg电议
1mg电议
5mg电议

产品介绍
An active metabolite of estrone
Cas No.58562-33-7
别名4-甲氧基雌酮
Canonical SMILESC[C@@]12[C@](CCC2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C(OC)=C4CC3
分子式C19H24O3
分子量300.4
溶解度Chloroform: slightly soluble,Methanol: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4-methoxy Estrone is an active metabolite of the endogenous estrogen estrone .1It is formed from estrone by catechol-O-methyltransferase (COMT). 4-methoxy Estrone (10 and 100 nM) increases the proliferation of human umbilical vein endothelial cells (HUVECs).2

1.Dawling, S., Roodi, N., Mernaugh, R.L., et al.Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: Comparison of wild-type and variant COMT isoformsCancer Res.61(18)6716-6722(2001) 2.Lippert, C., Seeger, H., Mueck, A.O., et al.The effects of A-ring and D-ring metabolites of estradiol on the proliferation of vascular endothelial cellsLife Sci.67(13)1653-1658(2000)