CRT 0066854 hydrochloride 是一种有效的选择性非典型 PKCs 抑制剂。
| Cas No. | 2250019-91-9 |
| Canonical SMILES | N[C@@H](CC1=CC=CC=C1)CNC2=C3C4=C(SC3=NC(C5=CC=NC=C5)=N2)CCCC4.Cl.Cl |
| 分子式 | C24H25N5S.2HCl |
| 分子量 | 488.48 |
| 溶解度 | water|48.85|100|DMSO|48.85|100| |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Protein kinase C (PKC) inhibitor. Inhibits PKCΙ and PKCζ; (IC50 values are 132 and 639 nM, respectively). Restores polarized morphogenesis in oncogene expressing MDCK cells, decreases colony formation in HeLa cells and inhibits lethal giant larvae 2 (LLGL2) phosphorylation. |
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