生物活性
PMPA是神经肽酶N-乙酰化的α-连接的酸性二肽酶(NAALADase)的有效抑制剂,NAALADase是一种膜结合肽酶,可水解主要的脑肽N-乙酰基-L-天冬氨酸-L-谷氨酸(NAAG。
化学数据
目录号 | A15310 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 226.12 |
Formula | C6H11O7P |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 173039-10-6 |
SMILES | C(CC(=O)O)C(CP(=O)(O)O)C(=O)O |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 44.22 mL | 221.12 mL | 442.24 mL |
0.5 mM | 8.84 mL | 44.22 mL | 88.45 mL |
1 mM | 4.42 mL | 22.11 mL | 44.22 mL |
5 mM | 0.88 mL | 4.42 mL | 8.84 mL |
*The above data is based on the productmolecular weight 226.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.