CAS NO: | 4434-05-3 |
包装: | 5mg |
市场价: | 4500元 |
Coumermycin A1 是一种 JAK2 信号激活剂。Coumermycin A1 抑制 DNA 旋转酶 (DNA Gyrase),从而抑制细菌的细胞分裂。
Cas No. | 4434-05-3 |
别名 | 香豆霉素 |
分子式 | C55H59N5O20 |
分子量 | 1110.08 |
溶解度 | DMSO : 50 mg/mL (45.04 mM; Need ultrasonic and warming) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1-induced-JAK2 signal activation increases the mRNA level of SCOS2, but reducea leptin receptor mRNA level[1]. [1]. Tiantian Zhang, et al. SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes. Research Article. |