CAS NO: | 2411819-82-2 |
包装: | 10mg |
市场价: | 13050元 |
Cas No. | 2411819-82-2 |
分子式 | C18H18F3N5O2S |
分子量 | 425.43 |
溶解度 | DMSO : 100 mg/mL (235.06 mM; Need ultrasonic) |
储存条件 | 4°C, away from moisture and light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | NBD-14270, a pyridine analogue, is a potentHIV-1entry antagonist with anIC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100 μM)[1][2]. NBD-14270 has anti-HIV-1 activity (IC50=0.16 μM ) and Cytotoxicity (CC50=109.3 μM) in single-cycle (TZM-bl Cells) assay[1]. |