| CAS NO: | 2064121-65-7 |
| 包装: | 10mg |
| 市场价: | 8550元 |
| Cas No. | 2064121-65-7 |
| 别名 | BAY-2433334 |
| 分子式 | C26H21ClF4N6O4 |
| 分子量 | 592.93 |
| 溶解度 | DMSO : ≥ 250 mg/mL (421.63 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Asundexian (BAY 2433334) is an orally activecoagulation factor Xia (FXIa)inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with anIC50of 1 nM[1]. Asundexian displays potent anticoagulant activity in vitro in human and rabbit plasma and antithrombotic efficacy in vivo in a rabbit arterial thrombosis model[1]. |
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